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Sofosbuvir

Paul A. Pham, Pharm.D., David L. Thomas, M.D., M.P.H., Janessa M. Smith, Pharm.D. BCPS
Sofosbuvir is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Treatment of HCV genotype 1, 2, 3 or 4 as a component of a combination antiviral treatment regimen
  • Indicated in patients with hepatocellular carcinoma, those awaiting liver transplantation, and those with HCV/HIV-1 co-infection

NON-FDA APPROVED USES

  • In combination with an HCV active antiviral regimen, sofosbuvir’s (SOF) efficacy has been established in patients with HCV genotype 5 and 6

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Last updated: April 6, 2017

Citation

Pham, Paul A, et al. "Sofosbuvir." Johns Hopkins ABX Guide, The Johns Hopkins University, 2017. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540635/all/Sofosbuvir.
Pham PA, Thomas DL, Smith JM. Sofosbuvir. Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540635/all/Sofosbuvir. Accessed April 26, 2019.
Pham, P. A., Thomas, D. L., & Smith, J. M. (2017). Sofosbuvir. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540635/all/Sofosbuvir
Pham PA, Thomas DL, Smith JM. Sofosbuvir [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. [cited 2019 April 26]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540635/all/Sofosbuvir.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Sofosbuvir ID - 540635 A1 - Pham,Paul,Pharm.D. AU - Thomas,David,M.D., M.P.H. AU - Smith,Janessa,Pharm.D. BCPS Y1 - 2017/04/06/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540635/all/Sofosbuvir PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -