Sofosbuvir

Paul A. Pham, Pharm.D., David L. Thomas, M.D., M.P.H., Janessa M. Smith, Pharm.D. BCPS
Sofosbuvir is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Treatment of HCV genotype 1, 2, 3 or 4 as a component of a combination antiviral treatment regimen
  • Indicated in patients with hepatocellular carcinoma, those awaiting liver transplantation, and those with HCV/HIV-1 co-infection

NON-FDA APPROVED USES

  • In combination with an HCV active antiviral regimen, sofosbuvir’s (SOF) efficacy has been established in patients with HCV genotype 5 and 6

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Last updated: April 6, 2017