Sofosbuvir

Paul G. Auwaerter, M.D., Janessa M. Smith, Pharm.D. BCPS

INDICATIONS

INDICATIONS

INDICATIONS

FDA

FDA

FDA

  • Treatment of HCV genotype 1, 2, 3, or 4 as a component of a combination antiviral treatment regimen
    • Indicated in patients with hepatocellular carcinoma, those awaiting liver transplantation, and those with HCV/HIV-1 co-infection
  • Pediatric patients 3 years of age and older with genotype 2 or 3 chronic HCV infection without cirrhosis or with compensated cirrhosis in combination with ribavirin

NON-FDA APPROVED USES

NON-FDA APPROVED USES

NON-FDA APPROVED USES

  • In combination with an HCV active antiviral regimen, sofosbuvir’s (SOF) efficacy has been established in patients with HCV genotypes 5 and 6

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