Human Metapneumovirus

Valeria Fabre, M.D., Paul G. Auwaerter, M.D.


  • Human metapneumovirus (hMPV): negative-sense, single-strand RNA virus, member of Paramyxoviridae described in 2001--closely related to respiratory syncytial virus (RSV).
    • Taxonomy: order Mononegavirales, family Paramyxoviridae, genus Metapneumovirus (first human member), subfamily Pneumovirinae.
  • Genetically similar to avian pneumoviruses types C, B and A.
  • Human pathophysiology: replication within the respiratory epithelium, hyaline membrane.

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Last updated: March 8, 2020