Human Metapneumovirus

Valeria Fabre, M.D.

MICROBIOLOGY

Human metapneumovirus (hMPV): negative-sense, single-stranded RNA virus, member of Paramyxoviridae described in 2001--closely related to respiratory syncytial virus (RSV).
- Taxonomy: order Mononegavirales, family Paramyxoviridae, genus Metapneumovirus (first human member), subfamily Pneumovirinae.
Genetically similar to avian pneumoviruses types C, B and A.
Human pathophysiology: replication within the respiratory epithelium within the hyaline membrane.

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