Johns Hopkins ABX Guide
Streptococcal Toxic Shock Syndrome
PATHOGENS
- Streptococcus pyogenes (Group A, GAS)
- S. pyogenes produces exotoxins SPEA, SPEB, and SPEC.
- These toxins are superantigens capable of activating up to 25% of T cells. Therapy selected to stop toxin production.
- S. pyogenes produces exotoxins SPEA, SPEB, and SPEC.
- Other Streptococcus species (described)
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Last updated: December 2, 2019
Citation
Blankson, Joel N. "Streptococcal Toxic Shock Syndrome." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540522/all/Streptococcal_Toxic_Shock_Syndrome.
Blankson JN. Streptococcal Toxic Shock Syndrome. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540522/all/Streptococcal_Toxic_Shock_Syndrome. Accessed December 6, 2023.
Blankson, J. N. (2019). Streptococcal Toxic Shock Syndrome. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540522/all/Streptococcal_Toxic_Shock_Syndrome
Blankson JN. Streptococcal Toxic Shock Syndrome [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2023 December 06]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540522/all/Streptococcal_Toxic_Shock_Syndrome.
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