Streptococcal Toxic Shock Syndrome

Streptococcal Toxic Shock Syndrome is a topic covered in the Johns Hopkins ABX Guide.

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PATHOGENS

  • Streptococcus pyogenes (Group A, GAS)
    • S. pyogenes produces exotoxins SPEA, SPEB, and SPEC.
      • These toxins are superantigens capable of activating up to 25% of T cells. Therapy selected to stop toxin production.
  • Other Streptococcus species (described)

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Last updated: December 2, 2019