Respiratory syncytial virus
MICROBIOLOGY
- Negative-sense, single-strand, enveloped RNA virus.
- There are two subtypes (A and B). The severity may be similar between the two viruses.
- The scientific name is human orthopneumovirus.
- The synonym is human respiratory syncytial virus (hRSV), sometimes shortened to just RSV.
- Member of the Pneumoviridae family and Orthopneumovirus genus.
- RSV fusion protein facilitates the fusion of the viral envelope with the host cell membrane. This protein is a target for vaccines and anti-viral agents.
- In this section, we will refer to the virus that infects humans as RSV (although human orthopneumovirus is the International Committee on Taxonomy of Viruses preferred term).
- Transmission:
- There are no animal reservoirs for this virus.
- Spread via nasal or oral secretions, either directly via large droplets (and probably aerosolized particles) or indirectly through contact with contaminated hands and environmental surfaces (e.g., cribs, toys, doorknobs, tabletops)
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Last updated: September 8, 2024
Citation
Shoham, Shmuel. "Respiratory Syncytial Virus." Johns Hopkins ABX Guide, The Johns Hopkins University, 2024. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus.
Shoham S. Respiratory syncytial virus. Johns Hopkins ABX Guide. The Johns Hopkins University; 2024. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus. Accessed December 10, 2024.
Shoham, S. (2024). Respiratory syncytial virus. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus
Shoham S. Respiratory Syncytial Virus [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2024. [cited 2024 December 10]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus.
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