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Respiratory syncytial virus

John G. Bartlett, M.D., Shmuel Shoham, M.D.
Respiratory syncytial virus is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

  • Negative sense, single strand, enveloped RNA paramyxovirus.
    • Member of Paramyxoviridae, along with human metapneumovirus (hMPV), measles and mumps.
    • RSV is part of subfamily Pneumovirinae.
  • RSV fusion protein facilitates fusion of the viral envelope with the host cell membrane. This protein is a potential target for vaccines and anti-viral agents.
  • The virus that infects people is human RSV. There are no animal reservoirs for this virus.
    • Transmission is via nasal or oral secretions, either directly via large droplets (and probably aerosolized particles) or indirectly through contact with contaminated hands and environmental surfaces (e.g. cribs, toys, doorknobs, tabletops).

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Last updated: October 4, 2015

Citation

Bartlett, John G, and Shmuel Shoham. "Respiratory Syncytial Virus." Johns Hopkins ABX Guide, The Johns Hopkins University, 2015. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus.
Bartlett JG, Shoham S. Respiratory syncytial virus. Johns Hopkins ABX Guide. The Johns Hopkins University; 2015. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus. Accessed April 19, 2019.
Bartlett, J. G., & Shoham, S. (2015). Respiratory syncytial virus. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus
Bartlett JG, Shoham S. Respiratory Syncytial Virus [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2015. [cited 2019 April 19]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Respiratory syncytial virus ID - 540472 A1 - Bartlett,John,M.D. AU - Shoham,Shmuel,M.D. Y1 - 2015/10/04/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540472/all/Respiratory_syncytial_virus PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -