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Piperacillin + Tazobactam

Edina Avdic, Pharm.D., Paul A. Pham, Pharm.D.
Pediatric Dosing Author: Alice Jenh Hsu, PharmD, BCPS, AQ-ID

Piperacillin + Tazobactam is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

Gynecologic infections (pelvic inflammatory disease, post-partum endometritis)
Intra-abdominal infections (peritonitis, appendicitis, cholecystitis)
Skin and skin structure infections (including diabetic foot infections)
Community-acquired pneumonia
Nosocomial pneumonia

NON-FDA APPROVED USES

Endocarditis caused by Enterobacteriaceae and Pseudomonasspp. (usually in combination with aminoglycosides)
Aspiration pneumonia, lung abscess,empyema
Ventilator-associated pneumonia
Neutropenic fever
Bacteremia caused by Pseudomonas spp. or polymicrobial
Empiric therapy for variety infections where broad-spectrum agent is needed including sepsis (except for meningitis)

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Last updated: October 2, 2018

Citation

Avdic, Edina, and Paul A Pham. "Piperacillin + Tazobactam." Johns Hopkins ABX Guide, The Johns Hopkins University, 2018. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540434/all/Piperacillin_+_Tazobactam.

Avdic E, Pham PA. Piperacillin + Tazobactam. Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540434/all/Piperacillin_+_Tazobactam. Accessed April 18, 2019.

Avdic, E., & Pham, P. A. (2018). Piperacillin + Tazobactam. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540434/all/Piperacillin_+_Tazobactam

Avdic E, Pham PA. Piperacillin + Tazobactam [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. [cited 2019 April 18]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540434/all/Piperacillin_+_Tazobactam.

* Article titles in AMA citation format should be in sentence-case

TY - ELEC T1 - Piperacillin + Tazobactam ID - 540434 A1 - Avdic,Edina,Pharm.D. AU - Pham,Paul,Pharm.D. Y1 - 2018/10/02/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540434/all/Piperacillin_+_Tazobactam PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -