Piperacillin + Tazobactam

Caitlin Soto, PharmD, BCIDP, , Edina Avdic, Pharm.D.
Pediatric Dosing Author: Taylor Imburgia, PharmD, BCPPS

INDICATIONS

FDA

Gynecologic infections (pelvic inflammatory disease, postpartum endometritis)
Intra-abdominal infections (peritonitis, appendicitis, cholecystitis)
Skin and skin structure infections (including diabetic foot infections)
Community-acquired pneumonia
Nosocomial pneumonia

NON-FDA APPROVED USES

Endocarditis caused by Enterobacteriaceae and Pseudomonasspp. (usually in combination with aminoglycosides)
Aspiration pneumonia, lung abscess, empyema
Ventilator-associated pneumonia
Neutropenic fever
Bacteremia caused by Pseudomonas spp. or polymicrobial
Empiric therapy for a variety of infections where a broad-spectrum agent is needed, including sepsis (except for meningitis)

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