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Morganella is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

  • Facultative anaerobic Gram-negative rod.
    • Non-lactose fermenter in the same family as Proteus.
    • Environmentally ubiquitous, part of normal colonic flora.
    • "Urea splitter," but stones seen less frequently than Proteus due to less effective urease enzyme.
  • Morganella only has single member in its genus M. morganii, and two subspecies: M. morganii and M. sibonii, which differ only in trehalose fermentation.
  • Antimicrobial susceptibility:
    • Naturally resistant to penicillin, first-, second-generation cephalosporins, macrolides, sulfamethoxazole.
    • Beta-lactamase is inducible, chromosomal AmpC type.
    • Production of extended spectrum beta-lactamases, including carbapenemases Amber class B -such as New Delhi metallo-β-lactamase 1 (NDM-1)- and Amber class D -such as OXA-181- as well as fluoroquinolone resistance have been reported
    • Tigecycline not reliably effective due to ArcAB efflux pump, although may show synergy in vitro with other antimicrobials[6].

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Last updated: April 5, 2016

Citation

Fabre, Valeria. "Morganella." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540354/all/Morganella.
Fabre V. Morganella. Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540354/all/Morganella. Accessed April 23, 2019.
Fabre, V. (2016). Morganella. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540354/all/Morganella
Fabre V. Morganella [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 April 23]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540354/all/Morganella.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Morganella ID - 540354 A1 - Fabre,Valeria,M.D. Y1 - 2016/04/05/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540354/all/Morganella PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -