Johns Hopkins ABX Guide
Metronidazole
INDICATIONS
FDA
FDA
- Anaerobic infections: intra-abdominal infections, skin and skin structure infections, bone and joint infections
- Bacterial septicemia; endocarditis (caused by Bacteroides spp.)
- Gynecologic infections (endometritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection) in combination with agents active against Gram-negative urogenital flora.
- Lower respiratory tract infections (in combination with another agent with activity against microaerophilic Streptococcus)
- Adjunct treatment for gastritis and duodenal ulcer associated with Helicobacter pylori
- CNS infections (meningitis and brain abscess)
- Treatment of acute intestinal amebiasis and amebic liver abscess
- Treatment of symptomatic and asymptomatic trichomoniasis
- Bacterial vaginosis (vaginal gel)
- Acne rosacea (topical gel)
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Colitis, including C. difficile, Crohn’s flare
- Treatment of giardiasis and dracunculiasis
- Periodontal disease
- Elective colorectal surgery (classified as contaminated or potentially contaminated)
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Last updated: January 11, 2025
Citation
, Caitlin Soto, PharmD, BCIDP, and Kathryn Dzintars. "Metronidazole." Johns Hopkins ABX Guide, The Johns Hopkins University, 2025. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540346/all/Metronidazole.
C, Dzintars K. Metronidazole. Johns Hopkins ABX Guide. The Johns Hopkins University; 2025. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540346/all/Metronidazole. Accessed July 25, 2025.
, C., & Dzintars, K. (2025). Metronidazole. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540346/all/Metronidazole
C, Dzintars K. Metronidazole [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2025. [cited 2025 July 25]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540346/all/Metronidazole.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Metronidazole
ID - 540346
A1 - ,Caitlin Soto, PharmD, BCIDP,
AU - Dzintars,Kathryn,Pharm.D., BCPS
Y1 - 2025/01/11/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540346/all/Metronidazole
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -
