Eflornithine

Edina Avdic, Pharm.D., Paul A. Pham, Pharm.D.
Eflornithine is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Eflornithine (IV): no longer commercially available in the U.S.
  • Treatment of unwanted facial hair in women (topical cream)

NON-FDA APPROVED USES

  • African trypanosomiasis (sleeping sickness):Second-stage T. b. gambiense
    • Eflornithine is not effective against T. b. rhodesiense(East African form of the diseases)
    • Drug can be obtained from CDC by contacting the Division of Parasitic Diseases and Malaria (telephone, 404-718-4745; email, parasites@cdc.gov).

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Last updated: June 3, 2017