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Doxycycline

Kathryn Dzintars, Pharm.D., BCPS, Paul A. Pham, Pharm.D.

Doxycycline is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

Anthrax due to Bacillus anthracis
- Inhalation anthrax: Post-exposure prophylaxis or treatment (see "biodefense-anthrax")
- Treatment of cutaneous, gastrointestinal or oropharyngeal anthrax
Granuloma inguinale caused by Calymmatobacterium granulomatis
If PCN allergic
- Uncomplicated gonorrhea caused by Neisseria gonorrhoeae
- Syphilis caused by Treponema pallidum
- Yaws caused by Treponema pertenue
- Listeriosis due to Listeria monocytogenes
- Vincent’s infection caused by Fusobacterium fusiforme
- Actinomycosis caused by Actinomyces israelli
- Infections caused by Clostridial species
Psittacosis caused by Chlamydia psittaci
Relapsing fever caused by Borrelia recurrentis
Mycoplasma pneumoniae
Rocky mountain spotted fever (RMSF), typhus, Q fever, rickettsialpox, and tick fevers cased by Rickettsia species.
Sexually Transmitted Infections
- Uncomplicated urethral, endocervical or rectal infections caused by Chlamydia trachomatis
- Nongonococcal urethritis caused by Ureaplasma urealyticum
- Lymphogranuloma venereum caused by Chlamydia spp.
Trachoma, inclusion conjunctivitis cause by C. trachomatis.
Gram-negative infections caused by H. ducreyi, Y. pestis, F. tularensis, V. cholerae, C. fetus, Brucella spp., B. bacilliformis, C. granulomatis.

NON-FDA APPROVED USES

Lyme disease
Malaria prophylaxis
Community acquired pneumonia
Acute bacterial rhinosinusitis
Skin and soft tissue infections due to S. aureus

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Last updated: January 3, 2017

Citation

Dzintars, Kathryn, and Paul A Pham. "Doxycycline." Johns Hopkins ABX Guide, The Johns Hopkins University, 2017. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540178/all/Doxycycline.

Dzintars K, Pham PA. Doxycycline. Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540178/all/Doxycycline. Accessed April 18, 2019.

Dzintars, K., & Pham, P. A. (2017). Doxycycline. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540178/all/Doxycycline

Dzintars K, Pham PA. Doxycycline [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. [cited 2019 April 18]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540178/all/Doxycycline.

* Article titles in AMA citation format should be in sentence-case

TY - ELEC T1 - Doxycycline ID - 540178 A1 - Dzintars,Kathryn,Pharm.D., BCPS AU - Pham,Paul,Pharm.D. Y1 - 2017/01/03/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540178/all/Doxycycline PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -