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Daptomycin

Edina Avdic, Pharm.D.
Daptomycin is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

NON-FDA APPROVED USES

  • Endocarditis caused by Enterococcus spp. resistant to vancomcyin, penicillin and aminoglycosides[2]
  • VRE infections including BSI, intra-abdominal infections, urinary tract infections, SSTI
  • Alternative therapy:
    • Instead of vancomycin for left-sided native valve endocarditis caused by MSSA[2]
    • S. aureus and Enterococcus spp. prosthetic joint infections
    • S. aureus and Enterococcus spp. native vertebral osteomyelitis[5]
  • Note: daptomycin should not be used for treatment of pneumonia

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Last updated: April 8, 2019

Citation

Avdic, Edina. "Daptomycin." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540155/all/Daptomycin.
Avdic E. Daptomycin. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540155/all/Daptomycin. Accessed April 18, 2019.
Avdic, E. (2019). Daptomycin. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540155/all/Daptomycin
Avdic E. Daptomycin [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 April 18]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540155/all/Daptomycin.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Daptomycin ID - 540155 A1 - Avdic,Edina,Pharm.D. Y1 - 2019/04/08/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540155/all/Daptomycin PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -