Daptomycin
Edina Avdic, Pharm.D.
Pediatric Dosing Author:
Bethany Sharpless Chalk, Pharm.D., BCPPS
INDICATIONS
INDICATIONS
INDICATIONS
FDA
FDA
FDA
Complicated skin and skin structure infections
(caused by susceptible strains of Gram-positive microorganisms including MSSA and MRSA).
S. aureus
bacteremia, including those with right-sided
endocarditis
, caused by MSSA and MRSA
NON-FDA APPROVED USES
NON-FDA APPROVED USES
NON-FDA APPROVED USES
Endocarditis
caused by
Enterococcus
spp. resistant to vancomycin, penicillin and aminoglycosides
[2]
VRE infections including BSI,
intra-abdominal infections
, urinary tract infections, SSTI
Alternative therapy:
Instead of vancomycin for left-sided native valve endocarditis caused by MSSA
[2]
S. aureus
and
Enterococcus
spp.
prosthetic joint infections
S. aureus
and
Enterococcus
spp. native vertebral osteomyelitis
[9]
Note
: daptomycin should not be used for the treatment of pneumonia
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