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Cefepime

Kathryn Dzintars, Pharm.D., BCPS, Paul A. Pham, Pharm.D.
Pediatric Dosing Author: Alice Jenh Hsu, PharmD, BCPS, AQ-ID

Cefepime is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

Pneumonia caused by S. pneumoniae
- Including cases associated with concurrent bacteremia, P. aeruginosa, K. pneumoniaeor Enterobacter species.
Febrile neutropenia (empiric therapy)
Uncomplicated and complicated urinary tract infections including pyelonephritis (+/- bacteremia) caused by E. coli, K. pneumoniae, or P. mirabilis
Uncomplicated skin and skin-structure infections caused by MSSA or S. pyogenes.
Complicated intra-abdominal infections (in combination with metronidazole) caused by E. coli, viridans group streptococci, P. aeruginosa, K. pneumoniae, Enterobacter species, or B. fragilis.

NON-FDA APPROVED USES

Shunt infections, CNS
Appendicitis (with metronidazole)
Diverticulitis (with metronidazole)
Intra-abdominal abscess (with metronidazole)
Osteomyelitis, acute
Osteomyelitis, chronic
Diabetic foot infection (with metronidazole or clindamycin)
Hardware associated septic arthritis
Acute exacerbations of chronic bronchitis

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Last updated: October 2, 2018

Citation

Dzintars, Kathryn, and Paul A Pham. "Cefepime." Johns Hopkins ABX Guide, The Johns Hopkins University, 2018. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540090/all/Cefepime.

Dzintars K, Pham PA. Cefepime. Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540090/all/Cefepime. Accessed April 18, 2019.

Dzintars, K., & Pham, P. A. (2018). Cefepime. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540090/all/Cefepime

Dzintars K, Pham PA. Cefepime [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. [cited 2019 April 18]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540090/all/Cefepime.

* Article titles in AMA citation format should be in sentence-case

TY - ELEC T1 - Cefepime ID - 540090 A1 - Dzintars,Kathryn,Pharm.D., BCPS AU - Pham,Paul,Pharm.D. Y1 - 2018/10/02/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540090/all/Cefepime PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -