Johns Hopkins ABX Guide
Appendicitis
PATHOGENS
- Anticipate polymicrobial gastrointestinal flora:
- Enterobacterales (e.g. Escherichia coli, Klebsiella spp., and Enterobacter spp.)
- Anaerobes (e.g., Bacteroides spp.)
- Gram-positive cocci (e.g., Enterococcus spp, Streptococcus spp.)
- Fungi: (e.g., Candida spp) are less common
- In community-acquired infections, the major pathogens are Enterobacterales and anaerobes.
- In healthcare-associated infections or recent broad-spectrum antibiotic exposure, yeast, enterococci, resistant Gram-negative organisms, and Staphylococcus aureus may be seen.
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Last updated: November 9, 2022
Citation
Smith, Scott M, and Christopher F Carpenter. "Appendicitis." Johns Hopkins ABX Guide, The Johns Hopkins University, 2022. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540032/all/Appendicitis.
Smith SM, Carpenter CF. Appendicitis. Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540032/all/Appendicitis. Accessed July 25, 2025.
Smith, S. M., & Carpenter, C. F. (2022). Appendicitis. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540032/all/Appendicitis
Smith SM, Carpenter CF. Appendicitis [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. [cited 2025 July 25]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540032/all/Appendicitis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Appendicitis
ID - 540032
A1 - Smith,Scott,M.D.
AU - Carpenter,Christopher,M.D.
Y1 - 2022/11/09/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540032/all/Appendicitis
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -
