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Amikacin

Kathryn Dzintars, Pharm.D., BCPS, Paul A. Pham, Pharm.D.

Amikacin is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

Amikacin sulfate indicated in the short-term treatment of serious infections due to susceptible organisms
- [With the exception of uncomplicated UTI, aminoglycosides are generally used in combination for treatment of Pseudomonas aeruginosa.]
Bacterial septicemia (including neonatal sepsis)
Respiratory tract infections
Bones and joint infections
Central nervous system infections
Skin and soft tissue infections (including burns, post-operative infections)
Intra-abdominal infections
Complicated and recurrent urinary tract infections.

NON-FDA APPROVED USES

Pneumonia, Hospital-Acquired (in combination with a beta-lactam, beta-lactam/beta-lactamase inhibitor, or a third-/fourth-generation cephalosporin)
Tuberculosis
Non-tubercular mycobacterial (NTM) infections
Nocardia
Aerosolized amikacin has been used for the management of cystic fibrosis exacerbations

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Last updated: January 30, 2017

Citation

Dzintars, Kathryn, and Paul A Pham. "Amikacin." Johns Hopkins ABX Guide, The Johns Hopkins University, 2017. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540015/all/Amikacin.

Dzintars K, Pham PA. Amikacin. Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540015/all/Amikacin. Accessed March 24, 2019.

Dzintars, K., & Pham, P. A. (2017). Amikacin. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540015/all/Amikacin

Dzintars K, Pham PA. Amikacin [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. [cited 2019 March 24]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540015/all/Amikacin.

* Article titles in AMA citation format should be in sentence-case

TY - ELEC T1 - Amikacin ID - 540015 A1 - Dzintars,Kathryn,Pharm.D., BCPS AU - Pham,Paul,Pharm.D. Y1 - 2017/01/30/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540015/all/Amikacin PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -