Amikacin

Kathryn Dzintars, Pharm.D., BCPS
Pediatric Dosing Author: Lisa Hutchins, Pharm.D.
Amikacin is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Amikacin sulfate indicated in the short-term treatment of serious infections due to susceptible organisms
  • Bacterial septicemia (including neonatal sepsis)
  • Respiratory tract infections
  • Bone and joint infections
  • Central nervous system infections
  • Skin and soft tissue infections (including burns, postoperative infections)
  • Intra-abdominal infections
  • Complicated and recurrent urinary tract infections.

NON-FDA APPROVED USES

  • Pneumonia, Hospital-Acquired (in combination with a beta-lactam, beta-lactam/beta-lactamase inhibitor, or a third-/fourth-generation cephalosporin)
  • Tuberculosis
  • Non-tubercular mycobacterial (NTM) infections, MAI
  • Nocardia
  • Aerosolized amikacin has been used for the management of cystic fibrosis exacerbations

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INDICATIONS

FDA

  • Amikacin sulfate indicated in the short-term treatment of serious infections due to susceptible organisms
  • Bacterial septicemia (including neonatal sepsis)
  • Respiratory tract infections
  • Bone and joint infections
  • Central nervous system infections
  • Skin and soft tissue infections (including burns, postoperative infections)
  • Intra-abdominal infections
  • Complicated and recurrent urinary tract infections.

NON-FDA APPROVED USES

  • Pneumonia, Hospital-Acquired (in combination with a beta-lactam, beta-lactam/beta-lactamase inhibitor, or a third-/fourth-generation cephalosporin)
  • Tuberculosis
  • Non-tubercular mycobacterial (NTM) infections, MAI
  • Nocardia
  • Aerosolized amikacin has been used for the management of cystic fibrosis exacerbations

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Last updated: January 12, 2020