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Cyclic Vomiting Syndrome

Cyclic Vomiting Syndrome is a topic covered in the 5-Minute Pediatric Consult.

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  • Cyclic vomiting syndrome (CVS) is characterized by recurrent and stereotypical episodes of vomiting with intervening periods of normal health.
  • Essential clinical features of CVS are two or more periods of intense nausea and paroxysmal vomiting lasting hours to days within a 6-month period, return to baseline health between episodes, stereotypical episodes with regard to timing of symptoms and duration; as well as the absence of an identifiable organic cause for vomiting.


  • CVS commonly starts in early childhood with approximately 46% of children developing symptoms at ≤3 years of age.
  • Prevalence of 0.2–1% has been reported.
  • The syndrome is more common in Caucasians.

Commonly Associated Conditions

  • 2/3 of CVS patients have symptoms of irritable bowel syndrome (IBS).
  • 11% of CVS patients have migraine headaches and a third of patients later develop migraine headaches.

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Cabana, Michael D., editor. "Cyclic Vomiting Syndrome." 5-Minute Pediatric Consult, 8th ed., Wolters Kluwer, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/618177/all/Cyclic_Vomiting_Syndrome.
Cyclic Vomiting Syndrome. In: Cabana MD, ed. 5-Minute Pediatric Consult. 8th ed. Wolters Kluwer; 2019. https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/618177/all/Cyclic_Vomiting_Syndrome. Accessed April 23, 2019.
Cyclic Vomiting Syndrome. (2019). In Cabana, M. D. (Ed.), 5-Minute Pediatric Consult. Available from https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/618177/all/Cyclic_Vomiting_Syndrome
Cyclic Vomiting Syndrome [Internet]. In: Cabana MD, editors. 5-Minute Pediatric Consult. Wolters Kluwer; 2019. [cited 2019 April 23]. Available from: https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/618177/all/Cyclic_Vomiting_Syndrome.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Cyclic Vomiting Syndrome ID - 618177 ED - Cabana,Michael D, BT - 5-Minute Pediatric Consult UR - https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/618177/all/Cyclic_Vomiting_Syndrome PB - Wolters Kluwer ET - 8 DB - Pediatrics Central DP - Unbound Medicine ER -