Cyclic Vomiting Syndrome

Basics

Cyclic vomiting syndrome (CVS) is characterized by recurrent and stereotypical episodes of vomiting with intervening periods of normal health.
Essential clinical features of CVS are two or more periods of intense nausea and paroxysmal vomiting lasting hours to days within a 6-month period, return to baseline health between episodes, stereotypical episodes with regard to timing of symptoms and duration; as well as the absence of an identifiable organic cause for vomiting.

CVS commonly starts in early childhood with approximately 46% of children developing symptoms at ≤3 years of age.
Prevalence of 0.2–1% has been reported.
The syndrome is more common in Caucasians.

2/3 of CVS patients have symptoms of irritable bowel syndrome (IBS).
11% of CVS patients have migraine headaches and a third of patients later develop migraine headaches.

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