Johns Hopkins ABX Guide
Sulbactam and Durlobactam (Xacduro)
INDICATIONS
FDA
FDA
- Xacduro is a co-packaged product containing sulbactam, a beta-lactam antibiotic and beta-lactamase inhibitor, with durlobactam, a beta-lactamase inhibitor, that is approved for use in patients 18 years of age and older for the management of hospital-acquired pneumonia (HAP) or ventilator-associated pneumonia (VAP) caused by susceptible strains of Acinetobacter species.
- Sulbactam/durlobactam only has activity against Acinetobacter species and should NOT be used to treat HAP/VAP caused by other bacteria.
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Last updated: January 13, 2024
Citation
Dzintars, Kathryn. "Sulbactam and Durlobactam (Xacduro)." Johns Hopkins ABX Guide, The Johns Hopkins University, 2024. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540785/all/Sulbactam_and_Durlobactam__Xacduro_.
Dzintars K. Sulbactam and Durlobactam (Xacduro). Johns Hopkins ABX Guide. The Johns Hopkins University; 2024. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540785/all/Sulbactam_and_Durlobactam__Xacduro_. Accessed May 13, 2025.
Dzintars, K. (2024). Sulbactam and Durlobactam (Xacduro). In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540785/all/Sulbactam_and_Durlobactam__Xacduro_
Dzintars K. Sulbactam and Durlobactam (Xacduro) [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2024. [cited 2025 May 13]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540785/all/Sulbactam_and_Durlobactam__Xacduro_.
* Article titles in AMA citation format should be in sentence-case
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T1 - Sulbactam and Durlobactam (Xacduro)
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A1 - Dzintars,Kathryn,Pharm.D., BCPS
Y1 - 2024/01/13/
BT - Johns Hopkins ABX Guide
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PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
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