Johns Hopkins ABX Guide
Fexinidazole
INDICATIONS
FDA
FDA
- First-stage (hemolymphatic) and second-stage (meningoencephalitic) human African trypanosomiasis (HAT) due to T. brucei gambiensein patients 6 years of age and older who weigh at least 20 kg.
- Due to decreased efficacy observed in patients with severe second-stage HAT, fexinidazole should only be used in these patients if no other options are available.
- This drug was developed as part of the Drugs for Neglected Diseases initiative.
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Last updated: October 19, 2022
Citation
Dzintars, Kathryn . "Fexinidazole." Johns Hopkins ABX Guide, The Johns Hopkins University, 2022. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540775/all/Fexinidazole.
Dzintars K. Fexinidazole. Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540775/all/Fexinidazole. Accessed November 4, 2025.
Dzintars, K. (2022). Fexinidazole. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540775/all/Fexinidazole
Dzintars K. Fexinidazole [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. [cited 2025 November 04]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540775/all/Fexinidazole.
* Article titles in AMA citation format should be in sentence-case
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T1 - Fexinidazole
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A1 - Dzintars,Kathryn ,Pharm.D., BCPS
Y1 - 2022/10/19/
BT - Johns Hopkins ABX Guide
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PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
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