Johns Hopkins ABX Guide
Mediastinitis
PATHOGENS
Acute:
- Staphylococcus aureus
- Streptococcal species
- Gram-negative bacteria (especially post-surgical)
- Oral flora, including anaerobes (if evolved from esophageal perforation or deep space cervical infections)
- Candida species (rare)
Chronic:
- Histoplasma capsulatum (most common)
- Mycobacterium tuberculosis
- Coccidioides immitis
- Aspergillus
- Actinomyces
- Wucheria bancrofti
- This may also be due to noninfectious etiologies.
- Sarcoidosis
- Rheumatoid arthritis
- IgG-4 disease
- ANCA-related vasculitis
- Lymphoma-related
- Radiation
- Drug therapy (methysergide)
- Idiopathic: if etiology is undetermined.
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Last updated: May 6, 2023
Citation
Auwaerter, Paul G. "Mediastinitis." Johns Hopkins ABX Guide, The Johns Hopkins University, 2023. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540767/all/Mediastinitis.
Auwaerter PG. Mediastinitis. Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540767/all/Mediastinitis. Accessed April 28, 2024.
Auwaerter, P. G. (2023). Mediastinitis. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540767/all/Mediastinitis
Auwaerter PG. Mediastinitis [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. [cited 2024 April 28]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540767/all/Mediastinitis.
* Article titles in AMA citation format should be in sentence-case
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T1 - Mediastinitis
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A1 - Auwaerter,Paul,M.D.
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BT - Johns Hopkins ABX Guide
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PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
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