Prevotella
MICROBIOLOGY
- Non-motile Gram-negative bacillus may appear as slender rods or coccobacilli. [Fig 1and Fig 2]
- Usually recovered in anaerobic cultures.
- Previously described as a Bacteroides species, reclassified under the genus Prevotella.[16]
- Slow grower, some species require > 48 hrs incubation.
- As for all anaerobic bacteria, diagnosis of Prevotella spp. Infections require specialized techniques for transport, isolation, processing and identification.
- Prevotella identification in many laboratories is still based on phenotypic methods.
- Prevotella spp. are bile-sensitive and vancomycin-resistant in contrast to species of the Bacteroides fragilis group and Porphyromonas spp., respectively.[9]
- More than 50 species of Prevotella have been identified.
- In oral and head-and-neck infections, common isolates were Prevotella intermedia and Prevotella melaninogenica within the pigmented species and Prevotella oris and Prevotella oralis group within the non-pigmented species.[8]
- Prevotella species are intrinsically resistant to aminoglycosides, aztreonam, trimethoprim, sulfonamides and fosfomycin.[9]
There's more to see -- the rest of this topic is available only to subscribers.
Last updated: February 15, 2025
Citation
Kobayashi, Takaaki, and Paul G Auwaerter. "Prevotella." Johns Hopkins ABX Guide, The Johns Hopkins University, 2025. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540705/all/Prevotella.
Kobayashi T, Auwaerter PG. Prevotella. Johns Hopkins ABX Guide. The Johns Hopkins University; 2025. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540705/all/Prevotella. Accessed April 3, 2025.
Kobayashi, T., & Auwaerter, P. G. (2025). Prevotella. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540705/all/Prevotella
Kobayashi T, Auwaerter PG. Prevotella [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2025. [cited 2025 April 03]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540705/all/Prevotella.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Prevotella
ID - 540705
A1 - Kobayashi,Takaaki,M.D.
AU - Auwaerter,Paul,M.D.
Y1 - 2025/02/15/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540705/all/Prevotella
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -