- Aerobic, gram-negative, lactose fermenter [Fig] and oxidase positive.
- Part of the family Alcaligenaceae in the Burkholderiales order.
- May grow anaerobically.
- Motile, has peritrichous (meaning evenly distributed) flagella.
- Has been cultured using MacConkey, Mueller-Hinton, NAC and Salmonella-Shigella agars.
- Found widely in the environment, including soil and waters fresh and brackish.
- It may be a component of normal GI flora.
- Known to be associated with biofilm formation and is found in humidifiers and well water.
- Intrinsic and acquired multi-drug resistance are common. Two main mechanisms:
- Multidrug efflux pumps
- Metallo-β-lactamases, most commonly OXA-114-like (chromosomal)
- A. xylosoxidans: most commonly implicated in active infections.
- Intrinsically resistant to aminoglycosides, aztreonam, tetracyclines, and many penicillins/cephalosporins.
- Formerly called Alcaligenes xylosoxidans.
- Many other species that MALDI-TOF MS may be most helpful to identify. Some of the most common isolates seen in human infection are:
- A. denitrificans
- A. dolens
- A. insuavis
- A. piechaudii
- A. ruhlandii
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Last updated: August 8, 2022
Auwaerter, Paul G. "Achromobacter Species." Johns Hopkins ABX Guide, The Johns Hopkins University, 2022. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540697/all/Achromobacter_species.
Auwaerter PG. Achromobacter species. Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540697/all/Achromobacter_species. Accessed June 7, 2023.
Auwaerter, P. G. (2022). Achromobacter species. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540697/all/Achromobacter_species
Auwaerter PG. Achromobacter Species [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. [cited 2023 June 07]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540697/all/Achromobacter_species.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Achromobacter species ID - 540697 A1 - Auwaerter,Paul,M.D. Y1 - 2022/08/08/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540697/all/Achromobacter_species PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -