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    Paracoccidioides brasiliensis

    Valeria Fabre, M.D.
    Paracoccidioides brasiliensis is a topic covered in the Johns Hopkins ABX Guide.

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    MICROBIOLOGY

    • Dimorphic fungus.
      • At 37°C appears as an oval to round yeast cell variable in size, 4-40 μm.
      • The classic "ship’s wheel" structure [Fig 1] represents a mother cell surrounded by narrow base budding daughter cells.
    • Four different phylogenetic species (S1, PS2, PS3, PS4) confined to particular endemic regions.
    • Autochthonous disease from southern Mexico to northern Argentina.
      • Countries where there have been no reports of paracoccidioidomycosis (PM) include:
        • Central America: Belize and Nicaragua
        • South America: Chile, French Guiana, Guiana, and Suriname
    • Paracoccidioides lutzzi causes a similar disease in humans, cases of PM due to P. lutzzi have only been reported in Brazil and Ecuador.

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    Last updated: May 30, 2016

    Citation

    Fabre, Valeria. "Paracoccidioides Brasiliensis." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540662/all/Paracoccidioides_brasiliensis.
    Fabre V. Paracoccidioides brasiliensis. Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540662/all/Paracoccidioides_brasiliensis. Accessed April 19, 2019.
    Fabre, V. (2016). Paracoccidioides brasiliensis. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540662/all/Paracoccidioides_brasiliensis
    Fabre V. Paracoccidioides Brasiliensis [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 April 19]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540662/all/Paracoccidioides_brasiliensis.
    * Article titles in AMA citation format should be in sentence-case
    TY - ELEC T1 - Paracoccidioides brasiliensis ID - 540662 A1 - Fabre,Valeria,M.D. Y1 - 2016/05/30/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540662/all/Paracoccidioides_brasiliensis PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -