Mycoplasma hominis

Valeria Fabre, M.D.
Mycoplasma hominis is a topic covered in the Johns Hopkins ABX Guide.

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  • Aerobic, fastidious organism; easier to cultivate than M. genitalium.
    • Differs from bacteria due to smaller size, presence of sterols in the membrane and lack of a cell wall. The latter characteristic makes them intrinsically resistant to β-lactams.
    • Differs from M. genitalium in that it is intrinsically resistant to 14-member macrolides (erythromycin and clarithromycin; see discussion below).
  • M. hominis grows on agar plates and broth cultures.
    • Visible colonies in 2 - 5 days.
    • Colonies have "fried egg" appearance on agar [Fig, denser in the center and less dense in the periphery].
  • Colonizes male and female genitourinary tract.

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Last updated: September 13, 2019