Encephalitis, Table 3
Diagnostic Criteria for Encephalitis and Encephalopathy
Major Criterion (required): |
Patients presenting to medical attention with altered mental status (defined as decreased or altered level of consciousness, lethargy or personality change) lasting ≥24 h with no alternative cause identified. |
Minor Criteria (2 required for possible encephalitis; ≥3 required for probable or confirmeda encephalitis): |
Documented fever ≥38° C (100.4°F) within the 72 h before or after presentationb |
Generalized or partial seizures not fully attributable to a preexisting seizure disorderc |
New onset of focal neurologic findings |
CSF WBC count ≥5/cubic mmd |
Abnormality of brain parenchyma on neuroimaging suggestive of encephalitis that is either new from prior studies or appears acute in onsete |
Abnormality on electroencephalography that is consistent with encephalitis and not attributable to another cause.f |
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