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Ureaplasma urealyticum

Ureaplasma urealyticum is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

  • Among the smallest of bacteria; lacks a cell well. Member of Mycoplasmataceae family.
    • May be normal component of male/female genital flora.
    • Found normally on genital mucosal surfaces in majority of sexually active adults.
  • Media for growth must contain cholesterol (tissue culture conditions needed); organism hydrolyzes urea--hence its name.
    • Usually sub-cultured to blood agar plate for identification. Ureaplasma colonies are of a pinpoint character.
  • 17 species recognized from humans, with 4 as most often implicated: usually species can only distinguish in clinical samples by PCR.
    • Ureaplasma parvum (Up): most commonly isolated, considered vaginal commensal.
    • Ureaplasma urealyticum (Uu): considered most virulent, especially in urethritis afflicting men, although one large study found a lack of association with symptoms[2].
      • Association with other disease entities such as PID is less robust.

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Last updated: April 5, 2016

Citation

Auwaerter, Paul G. "Ureaplasma Urealyticum." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum.
Auwaerter PG. Ureaplasma urealyticum. Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum. Accessed March 24, 2019.
Auwaerter, P. G. (2016). Ureaplasma urealyticum. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum
Auwaerter PG. Ureaplasma Urealyticum [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 March 24]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Ureaplasma urealyticum ID - 540617 A1 - Auwaerter,Paul,M.D. Y1 - 2016/04/05/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -