Ureaplasma urealyticum
MICROBIOLOGY
- Among the smallest bacteria, it lacks a cell wall [Fig 1].
- Member of Mycoplasmataceae family.
- It may be a normal component of male/female genital flora.
- Found generally on genital mucosal surfaces in the majority of sexually active adults.
- Media for growth must contain cholesterol (tissue culture conditions needed); the organism hydrolyzes urea--hence its name.
- Usually sub-cultured to blood agar plate for identification. Ureaplasma colonies are pinpoint-sized.
- Seventeen species are recognized from humans, with four as most often implicated: usually, species can only distinguish in clinical samples by PCR.
- Ureaplasma parvum (Up): most commonly isolated, considered vaginal commensal.
- Ureaplasma urealyticum (Uu): considered most virulent, especially in urethritis, afflicting men, although one large study found a lack of association with symptoms[6].
- Association with other disease entities, such as PID, is less robust.
- Ureaplasma parvum (Up): most commonly isolated, considered vaginal commensal.
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Last updated: February 15, 2023
Citation
Auwaerter, Paul G. "Ureaplasma Urealyticum." Johns Hopkins ABX Guide, The Johns Hopkins University, 2023. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum.
Auwaerter PG. Ureaplasma urealyticum. Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum. Accessed December 11, 2024.
Auwaerter, P. G. (2023). Ureaplasma urealyticum. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum
Auwaerter PG. Ureaplasma Urealyticum [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. [cited 2024 December 11]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540617/all/Ureaplasma_urealyticum.
* Article titles in AMA citation format should be in sentence-case
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T1 - Ureaplasma urealyticum
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BT - Johns Hopkins ABX Guide
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PB - The Johns Hopkins University
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