- Parasites that are commonly found in the intestinal flora of humans.
- Molecular studies have documented numerous genotypes, including usually zoonotic organisms, so B. hominis infection in humans is likely more heterogeneous than suspected.
- Global presence is found also in animals, e.g., swine.
- Appears as a thick-walled cyst (6-40 μm) in human feces [Fig].
- Taxonomic classification is unclear. Based on RNA molecular analysis, B. hominis has been labeled as a stramenopile, similar to a large grouping of one and multi-celled protists such as algae, diatoms and slime molds. Confusion genomically also furthered as the organism has both a nuclear genome and organelle genome.
- B. hominis was historically used to denote infection, but likely a more diverse group of Blastocystis causes human infection.
- Suggest due to diversity, probably refer to Blastocystis spp. or Blastocystis spp. subtype n (n= subtype number, Stensvold classification).
- The lifecycle is not well understood; likely transmission through fecal-oral routes, with contaminated water a high suspect. Cysts may infect epithelial cells of the GI tract.
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Last updated: December 11, 2022
Auwaerter, Paul G. "Blastocystis." Johns Hopkins ABX Guide, The Johns Hopkins University, 2022. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540610/all/Blastocystis.
Auwaerter PG. Blastocystis. Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540610/all/Blastocystis. Accessed June 3, 2023.
Auwaerter, P. G. (2022). Blastocystis. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540610/all/Blastocystis
Auwaerter PG. Blastocystis [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. [cited 2023 June 03]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540610/all/Blastocystis.
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TY - ELEC T1 - Blastocystis ID - 540610 A1 - Auwaerter,Paul,M.D. Y1 - 2022/12/11/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540610/all/Blastocystis PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -