Johns Hopkins ABX Guide
Artemether/Lemefantrine
INDICATIONS
FDA
FDA
- Treatment of acute, uncomplicated malaria infections due to Plasmodium falciparum in patients with ≥ 5 kg.
- Manufacturer does not recommend use for the treatment of severe malaria or the prevention of P. falciparum malaria.
- Most recent CDC guidelines recommend artemether/lumefantrine use for the treatment of severe malaria following administration of IV artesunate or while waiting for IV artesunate to arrive from CDC (see CDC website)
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Treatment of severe malaria due to P. falciparum following administration of IV artesunate or while awaiting for IV artesunate to arrive from CDC.
- Treatment of uncomplicated P. vivax malaria (2015 WHO recommendations)[2].
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Last updated: June 6, 2019
Citation
Avdic, Edina. "Artemether/Lemefantrine." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540604/all/Artemether_Lemefantrine.
Avdic E. Artemether/Lemefantrine. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540604/all/Artemether_Lemefantrine. Accessed July 24, 2025.
Avdic, E. (2019). Artemether/Lemefantrine. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540604/all/Artemether_Lemefantrine
Avdic E. Artemether/Lemefantrine [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2025 July 24]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540604/all/Artemether_Lemefantrine.
* Article titles in AMA citation format should be in sentence-case
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T1 - Artemether/Lemefantrine
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A1 - Avdic,Edina,Pharm.D.
Y1 - 2019/06/06/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540604/all/Artemether_Lemefantrine
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
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