Zanamivir

Y. Vivian Tsai, Pharm.D., Paul G. Auwaerter, M.D.

INDICATIONS

FDA

  • Uncomplicated acute illness due to influenza A and B infection (patients ≥ 7 years of age with ≤ 48 hours of symptoms).
    • Clinical benefit is best established when treatment is initiated within 48 hours of symptom onset in uncomplicated influenza.
    • It is FDA-approved for treatment in patients aged 7 years and older, but use is limited by inhaled administration and is not recommended in patients with asthma, COPD, or other underlying airway disease.
  • Influenza prophylaxis in those 5 years of age or older.
    • Not proven effective for prophylaxis in nursing home residents.

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Last updated: September 6, 2026