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    Vibrio cholerae

    Paul G. Auwaerter, M.D.
    Vibrio cholerae is a topic covered in the Johns Hopkins ABX Guide.

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    MICROBIOLOGY

    • Aerobic, Gram-negative, comma-shaped bacillus.
      • Cary Blair media suggested for transport.
      • Selective thiosulfate–citrate–bile salts agar (TCBS) best used for culture.
    • Water-borne pathogen, humans usually acquire infection through ingesting contaminated water or food. Countries may have endemic infection (ongoing continuously often with spikes during rainy season) or epidemics.
      • V. cholerae serogroup O1, biotype El Tor, originated in Asia but has caused infection (seventh cholera pandemic) throughout Africa and South America for ~43 yrs.
      • Newer serogroup, O139 described in SE Asia in 1992 now endemic.
    • Isolates described with resistance to ampicillin, tetracycline, ampicillin, aminoglycosides, sulfonamides, fluoroquinolones and trimethoprim.
    • Non-01 V. cholerae strains (also water-borne, may be non-toxigenic) can rarely cause non-diarrheal illness such as bacteremia and wound infections especially in cirrhotics. Infections may be from fresh or brackish waters.

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    Last updated: January 3, 2018

    Citation

    Auwaerter, Paul G. "Vibrio Cholerae." Johns Hopkins ABX Guide, The Johns Hopkins University, 2018. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540585/all/Vibrio_cholerae.
    Auwaerter PG. Vibrio cholerae. Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540585/all/Vibrio_cholerae. Accessed April 21, 2019.
    Auwaerter, P. G. (2018). Vibrio cholerae. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540585/all/Vibrio_cholerae
    Auwaerter PG. Vibrio Cholerae [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. [cited 2019 April 21]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540585/all/Vibrio_cholerae.
    * Article titles in AMA citation format should be in sentence-case
    TY - ELEC T1 - Vibrio cholerae ID - 540585 A1 - Auwaerter,Paul,M.D. Y1 - 2018/01/03/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540585/all/Vibrio_cholerae PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -