Vibrio cholerae is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- Aerobic, Gram-negative, comma-shaped bacillus.
- Cary Blair media suggested for transport.
- Selective thiosulfate–citrate–bile salts agar (TCBS) best used for culture.
- Water-borne pathogen, humans usually acquire infection through ingesting contaminated water or food. Countries may have endemic infection (ongoing continuously often with spikes during rainy season) or epidemics.
- V. cholerae serogroup O1, biotype El Tor, originated in Asia but has caused infection (seventh cholera pandemic) throughout Africa and South America for ~43 yrs.
- Newer serogroup, O139 described in SE Asia in 1992 now endemic.
- Isolates described with resistance to ampicillin, tetracycline, ampicillin, aminoglycosides, sulfonamides, fluoroquinolones and trimethoprim.
- Non-01 V. cholerae strains (also water-borne, may be non-toxigenic) can rarely cause non-diarrheal illness such as bacteremia and wound infections especially in cirrhotics. Infections may be from fresh or brackish waters.
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Last updated: January 3, 2018
Citation
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TY - ELEC
T1 - Vibrio cholerae
ID - 540585
A1 - Auwaerter,Paul,M.D.
Y1 - 2018/01/03/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540585/all/Vibrio_cholerae
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -