Varicella Zoster- Hyperimmune globulin
INDICATIONS
FDA
FDA
- VZV post-exposure prophylaxis in high-risk individuals:
- Immunocompromised children and adults
- Newborns of mothers with varicella around the time of delivery
- Premature infants
- Infants < 1 year of age
- Adults without evidence of the immunity
- Pregnant women
- ACIP and AAP recommend administration of VariZIG as soon as possible after exposure and within 10 days[1]
- The ACIP and AAP recommendations for post-exposure prophylaxis:
- Immunocompromised patients without evidence of immunity.
- Newborn infants whose mothers have signs and symptoms of varicella around the time of delivery (i.e., 5 days before to 2 days after delivery).
- Hospitalized premature infants born at ≥ 28 weeks of gestation whose mothers do not have evidence of immunity to varicella.
- Hospitalized premature infants born at < 28 weeks of gestation or who weigh ≤1000 g at birth, regardless of their mother’s evidence of immunity to varicella.
- Pregnant women without evidence of immunity.
- The ACIP and AAP recommendations for post-exposure prophylaxis:
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Last updated: March 7, 2019
Citation
Avdic, Edina, and Paul A Pham. "Varicella Zoster- Hyperimmune Globulin." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540581/all/Varicella_Zoster__Hyperimmune_globulin.
Avdic E, Pham PA. Varicella Zoster- Hyperimmune globulin. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540581/all/Varicella_Zoster__Hyperimmune_globulin. Accessed October 14, 2024.
Avdic, E., & Pham, P. A. (2019). Varicella Zoster- Hyperimmune globulin. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540581/all/Varicella_Zoster__Hyperimmune_globulin
Avdic E, Pham PA. Varicella Zoster- Hyperimmune Globulin [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2024 October 14]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540581/all/Varicella_Zoster__Hyperimmune_globulin.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Varicella Zoster- Hyperimmune globulin
ID - 540581
A1 - Avdic,Edina,Pharm.D.
AU - Pham,Paul,Pharm.D.
Y1 - 2019/03/07/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540581/all/Varicella_Zoster__Hyperimmune_globulin
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -