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Tobramycin is a topic covered in the Johns Hopkins ABX Guide.

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Pediatrics Central

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  • UTI
  • Septicemia, including serious central nervous system infections (use in combination)
  • Lower respiratory tract infections (use in combination)
  • Complicated urinary tract infections
  • Intra-abdominal infections, including peritonitis (use in combination)
  • Skin, bone, and skin structure infections (use in combination)
  • Management of cystic fibrosis, with P. aeruginosa (as TOBI inhalation)
  • Treatment of ocular infections (uncomplicated conjunctivitis-ophthalmic solution)


  • Pneumonia, hospital-acquired (in combination with a beta-lactam, beta-lactam/beta-lactamase inhibitor, or a third/fourth-generation cephalosporin)
  • Pseudomonal infections (in combination with a beta-lactam, beta-lactam/beta-lactamase inhibitor, carbapenem or a third/fourth-generation cephalosporin)

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Last updated: November 2, 2015


Pham, Paul A, and John G Bartlett. "Tobramycin." Johns Hopkins ABX Guide, The Johns Hopkins University, 2015. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540556/all/Tobramycin.
Pham PA, Bartlett JG. Tobramycin. Johns Hopkins ABX Guide. The Johns Hopkins University; 2015. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540556/all/Tobramycin. Accessed April 26, 2019.
Pham, P. A., & Bartlett, J. G. (2015). Tobramycin. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540556/all/Tobramycin
Pham PA, Bartlett JG. Tobramycin [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2015. [cited 2019 April 26]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540556/all/Tobramycin.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Tobramycin ID - 540556 A1 - Pham,Paul,Pharm.D. AU - Bartlett,John,M.D. Y1 - 2015/11/02/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540556/all/Tobramycin PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -