Sinusitis (Rhinosinusitis)--Subacute/Chronic
PATHOGENS
- The bacteriology of chronic sinusitis is less well-defined than acute sinusitis (typically due to Streptococcus pneumonia, Haemophilus influenzae, and Moraxella catarrhalis).
- A multifactorial disease that, aside from infection, is thought to result from genetics, environmental or occupational exposures, allergies, and immunodeficiencies.
- Typical respiratory pathogens may cause acute exacerbations of chronic sinusitis noted above.
- Polymicrobial flora is typically found if sinuses are cultured, especially in patients with a history of sinus surgeries, but the role of recovered organisms is often unclear.
- Gram-negative organisms increased, and possibly anaerobes.
- Pseudomonas aeruginosa and Staphylococcus aureus are more common in nosocomial and immunocompromised infections.
- Controversy exists over the role of fungi in chronic sinusitis.
- The suggestion is that fungal elements may incite an eosinophil-mediated immune response in sinonasal mucosa.
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Last updated: April 15, 2023
Citation
Auwaerter, Paul G, and Andrew Victores. "Sinusitis (Rhinosinusitis)--Subacute/Chronic." Johns Hopkins ABX Guide, The Johns Hopkins University, 2023. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540505/all/Sinusitis__Rhinosinusitis___Subacute_Chronic.
Auwaerter PG, Victores A. Sinusitis (Rhinosinusitis)--Subacute/Chronic. Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540505/all/Sinusitis__Rhinosinusitis___Subacute_Chronic. Accessed August 31, 2024.
Auwaerter, P. G., & Victores, A. (2023). Sinusitis (Rhinosinusitis)--Subacute/Chronic. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540505/all/Sinusitis__Rhinosinusitis___Subacute_Chronic
Auwaerter PG, Victores A. Sinusitis (Rhinosinusitis)--Subacute/Chronic [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. [cited 2024 August 31]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540505/all/Sinusitis__Rhinosinusitis___Subacute_Chronic.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Sinusitis (Rhinosinusitis)--Subacute/Chronic
ID - 540505
A1 - Auwaerter,Paul,M.D.
AU - Victores,Andrew,M.D.
Y1 - 2023/04/15/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540505/all/Sinusitis__Rhinosinusitis___Subacute_Chronic
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -