Johns Hopkins ABX Guide
Rhinovirus
Rhinovirus is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- Rhinovirus (RV) is a single-strand, non-enveloped positive-sense RNA virus; member of the Picornaviridae family of viruses.
- Over 105 serologic virus types. Human rhinovirus is responsible for up to 80% of common colds.
- Species include RV-A (adults > children), RV-B (least common) and RV-C (new species, often more severe or disseminated in children)
- Rhinoviruses gain entry via the upper respiratory tract binding to ICAM-1 (intracellular adhesion molecule -1) receptors on epithelial cells lining the respiratory tract. Chemokines and cytokines cause inflammation as a consequence of viral infection causing local symptoms.
- Involvement of cell receptor believed to account for part of the host effect and pathogenesis.
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Last updated: September 6, 2019
Citation
Auwaerter, Paul. "Rhinovirus." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540476/all/Rhinovirus.
Auwaerter P. Rhinovirus. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540476/all/Rhinovirus. Accessed October 19, 2019.
Auwaerter, P. (2019). Rhinovirus. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540476/all/Rhinovirus
Auwaerter P. Rhinovirus [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 October 19]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540476/all/Rhinovirus.
* Article titles in AMA citation format should be in sentence-case
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