Rhinovirus is a topic covered in the Johns Hopkins ABX Guide.

To view the entire topic, please or .

Pediatrics Central™ is an all-in-one application that puts valuable medical information, via your mobile device or the web, in the hands of clinicians treating infants, children, and adolescents. Explore these free sample topics:

-- The first section of this topic is shown below --

MICROBIOLOGY

  • Rhinovirus (RV) is a single-strand, non-enveloped positive-sense RNA virus; member of the Picornaviridae family of viruses.
  • Over 105 serologic virus types. Human rhinovirus is responsible for up to 80% of common colds.
    • Species include RV-A (adults > children), RV-B (least common) and RV-C (new species, often more severe or disseminated in children)
  • Rhinoviruses gain entry via the upper respiratory tract binding to ICAM-1 (intracellular adhesion molecule -1) receptors on epithelial cells lining the respiratory tract. Chemokines and cytokines cause inflammation as a consequence of viral infection causing local symptoms.
    • Involvement of cell receptor believed to account for part of the host effect and pathogenesis.

-- To view the remaining sections of this topic, please or --

MICROBIOLOGY

  • Rhinovirus (RV) is a single-strand, non-enveloped positive-sense RNA virus; member of the Picornaviridae family of viruses.
  • Over 105 serologic virus types. Human rhinovirus is responsible for up to 80% of common colds.
    • Species include RV-A (adults > children), RV-B (least common) and RV-C (new species, often more severe or disseminated in children)
  • Rhinoviruses gain entry via the upper respiratory tract binding to ICAM-1 (intracellular adhesion molecule -1) receptors on epithelial cells lining the respiratory tract. Chemokines and cytokines cause inflammation as a consequence of viral infection causing local symptoms.
    • Involvement of cell receptor believed to account for part of the host effect and pathogenesis.

There's more to see -- the rest of this topic is available only to subscribers.

Last updated: September 6, 2019