Johns Hopkins ABX Guide
Pyrimethamine + sulfadoxine
INDICATIONS
FDA
FDA
- No longer available in the U.S.
- Prophylaxis and treatment of chloroquine-resistant malaria.
- Malaria (acute) in combination with sulfadoxine and quinine in treating chloroquine-resistant Plasmodium falciparum malaria.
- Resistance is prevalent worldwide (not recommended as a prophylactic agent for travelers to most areas).
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Last updated: December 11, 2022
Citation
Auwaerter, Paul G, and Paul A Pham. "Pyrimethamine + Sulfadoxine." Johns Hopkins ABX Guide, The Johns Hopkins University, 2022. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540463/10/Pyrimethamine_+_sulfadoxine.
Auwaerter PG, Pham PA. Pyrimethamine + sulfadoxine. Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540463/10/Pyrimethamine_+_sulfadoxine. Accessed October 31, 2025.
Auwaerter, P. G., & Pham, P. A. (2022). Pyrimethamine + sulfadoxine. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540463/10/Pyrimethamine_+_sulfadoxine
Auwaerter PG, Pham PA. Pyrimethamine + Sulfadoxine [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. [cited 2025 October 31]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540463/10/Pyrimethamine_+_sulfadoxine.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Pyrimethamine + sulfadoxine
ID - 540463
A1 - Auwaerter,Paul,M.D.
AU - Pham,Paul,Pharm.D.
Y1 - 2022/12/11/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540463/10/Pyrimethamine_+_sulfadoxine
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -
