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- Aerobic, Gram-negative, urease-splitting rod. It is a non-lactose fermenter, indole-negative, oxidase-negative but catalase- and nitrate-positive.
- "Swarms" on moist agar (many flagella per organism, see video as an example).
- The second most commonly isolated Enterobacteriaceae after E. coli in many series.
- Most common species: P. mirabilis (indole negative) causes 90% of infections.
- Other Proteus spp. are indole positive, e.g., P. vulgaris and P. penneri.
- Proteus rettgari now a member ofProvidencia spp., properly Providencia rettgari, often a highly resistant organism.
- Can raise urine pH due to urea-splitting activity.
- P. mirabilis is usually resistant to tetracycline and nitrofurantoin, while 10-20% are resistant to ampicillin or cephalexin. P. vulgaris usually resistant to ampicillin or cephalexin/cefazolin.
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Last updated: June 6, 2019
Auwaerter, Paul. "Proteus Species." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540454/all/Proteus_species.
Auwaerter P. Proteus species. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540454/all/Proteus_species. Accessed October 21, 2019.
Auwaerter, P. (2019). Proteus species. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540454/all/Proteus_species
Auwaerter P. Proteus Species [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 October 21]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540454/all/Proteus_species.
TY - ELEC
T1 - Proteus species
ID - 540454
A1 - Auwaerter,Paul,M.D.
Y1 - 2019/06/06/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540454/all/Proteus_species
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine