Proteus species
MICROBIOLOGY
- Aerobic, Gram-negative, urease-splitting rod. It is a non-lactose fermenter, indole-negative, oxidase-negative but catalase- and nitrate-positive.
- Most common species: P. mirabilis (indole negative) causes 90% of infections.
- Other Proteus spp. are indole positive, e.g., P. vulgaris and P. penneri.
- Proteus rettgari now a member of Providencia spp., properly Providencia rettgari, often a highly resistant organism.
- It can raise urine pH due to urea-splitting activity.
- Other organisms commonly capable: Pseudomonas aeruginosa, Klebsiella pneumoniae, and Providencia species
- P. mirabilis is usually inherently resistant to tetracycline, colistin and nitrofurantoin, while 10-20% are resistant to ampicillin or cephalexin. P. vulgaris usually resistant to ampicillin or cephalexin/cefazolin.
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Last updated: May 30, 2021
Citation
Auwaerter, Paul. "Proteus Species." Johns Hopkins ABX Guide, The Johns Hopkins University, 2021. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540454/3.2/Proteus_species.
Auwaerter P. Proteus species. Johns Hopkins ABX Guide. The Johns Hopkins University; 2021. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540454/3.2/Proteus_species. Accessed December 1, 2024.
Auwaerter, P. (2021). Proteus species. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540454/3.2/Proteus_species
Auwaerter P. Proteus Species [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2021. [cited 2024 December 01]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540454/3.2/Proteus_species.
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T1 - Proteus species
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