Johns Hopkins ABX Guide
Cutibacterium (Propionibacterium) species
Cutibacterium (Propionibacterium) species is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- Previously termed Proprionibacterium
- Major human pathogens: many species, generally the two below represent majority of isolates. Member of Proprionibacteriaeceae.
- Cutibacterium acnes
- Cutibacterium avidum
- Major human pathogens: many species, generally the two below represent majority of isolates. Member of Proprionibacteriaeceae.
- Gram-positive pleomorphic rod that grows best anaerobically [Fig].
- Usually inhabits human skin, sebaceous glands, nasopharynx, GI/GU tracts.
- Generally sensitive to beta-lactams and resistant to aminoglycosides.
- Slow growth, often >5-6d.
- Incubation time, may require up to 14d to recover clinically significant isolates from prosthetic joint infections, for example.
- Reclassification of Proprionibacterium species as originally described due to the bacteria producing propionic acid as fermentation product. Bacteria seen in wide range of conditions: including cheeses (Swiss), ruminants stomachs, human skin. Based on 16s ribosomal analysis, this is now divided into the following:
- Acidipropionibacterium gen. nov.
- Cutibacterium gen nov.
- Pseudopropionibacteriumg en. nov.
- Propionibacterium (amended description of the genus)
-- To view the remaining sections of this topic, please log in or purchase a subscription --
MICROBIOLOGY
- Previously termed Proprionibacterium
- Major human pathogens: many species, generally the two below represent majority of isolates. Member of Proprionibacteriaeceae.
- Cutibacterium acnes
- Cutibacterium avidum
- Major human pathogens: many species, generally the two below represent majority of isolates. Member of Proprionibacteriaeceae.
- Gram-positive pleomorphic rod that grows best anaerobically [Fig].
- Usually inhabits human skin, sebaceous glands, nasopharynx, GI/GU tracts.
- Generally sensitive to beta-lactams and resistant to aminoglycosides.
- Slow growth, often >5-6d.
- Incubation time, may require up to 14d to recover clinically significant isolates from prosthetic joint infections, for example.
- Reclassification of Proprionibacterium species as originally described due to the bacteria producing propionic acid as fermentation product. Bacteria seen in wide range of conditions: including cheeses (Swiss), ruminants stomachs, human skin. Based on 16s ribosomal analysis, this is now divided into the following:
- Acidipropionibacterium gen. nov.
- Cutibacterium gen nov.
- Pseudopropionibacteriumg en. nov.
- Propionibacterium (amended description of the genus)
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Last updated: December 6, 2017
Citation
Auwaerter, Paul. "Cutibacterium (Propionibacterium) Species." Johns Hopkins ABX Guide, The Johns Hopkins University, 2017. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540453/3.0/Cutibacterium__Propionibacterium__species.
Auwaerter P. Cutibacterium (Propionibacterium) species. Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540453/3.0/Cutibacterium__Propionibacterium__species. Accessed March 3, 2021.
Auwaerter, P. (2017). Cutibacterium (Propionibacterium) species. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540453/3.0/Cutibacterium__Propionibacterium__species
Auwaerter P. Cutibacterium (Propionibacterium) Species [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. [cited 2021 March 03]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540453/3.0/Cutibacterium__Propionibacterium__species.
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PB - The Johns Hopkins University
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