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Parainfluenza virus

Parainfluenza virus is a topic covered in the Johns Hopkins ABX Guide.

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  • RNA enveloped (single strand, negative sense) virus w/ 5 antigenically distinct types: human parainfluenza virus types HPIV, HPIV-1, HPIV-2, HPIV-3, HPIV-4A/4B.
  • Viruses are members of the paramyxovirus family with two different genera:
    • HPIV-1, HPIV-3 belong to the Respirovirus genus.
      • HPIV-1: cause of croup in children with tendency to see more cases in fall season of odd-numbered years.
      • HPIV-3: cause of respiratory infections year-round especially when HPIV-1 and HPIV-2 not especially active, but more often seen in spring and early summer.
    • HPIV-2, HPIV-4 belong to the Rubulavirus genus.
      • HPIV-2: cause of croup in children, less common than HPIV-1 or HPIV-3, most cases seen in fall yearly.
      • HPIV-4: patterns are not well characterized.

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Last updated: September 11, 2018


Auwaerter, Paul G. "Parainfluenza Virus." Johns Hopkins ABX Guide, The Johns Hopkins University, 2018. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540415/all/Parainfluenza_virus.
Auwaerter PG. Parainfluenza virus. Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540415/all/Parainfluenza_virus. Accessed April 23, 2019.
Auwaerter, P. G. (2018). Parainfluenza virus. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540415/all/Parainfluenza_virus
Auwaerter PG. Parainfluenza Virus [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. [cited 2019 April 23]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540415/all/Parainfluenza_virus.
* Article titles in AMA citation format should be in sentence-case
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