Other atypical mycobacteria
MICROBIOLOGY
- M. celatum: slow growing (3-8 wks to culture), non-photochromogenic.
- It may cause false-positive M. tuberculosis direct (MTD) test or ribosomal RNA test.
- Found widely in the environment (soil, water, dust).
- M. genavense: very slow grower (42d average); difficult to grow; alert lab if M. genavense suspected.
- Consider if AFB is growing poorly and Mtb, MAI probe negative.
- Found in bird populations and ferrets.
- Antimicrobial testing is often problematic due to poor culture growth.
- M. haemophilum: slow growing; alert lab if suspected since it requires hemin or iron to grow in culture and grows best at 28-30°C.
- M. malmoense: slow growing; most clinical isolates/reports are from northern Europe.
- M. mucogenicum: rapid grower (< 7 days in culture); sporadic contaminant in respiratory samples; water is the environmental reservoir.
- Previously known as M. chelonae-like organism.
- M. simiae: growth may take 4-6 weeks on LJ slants.
- M. szulgai: scotochromogen at 37ºC and a photochromogen at 25ºC.
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Last updated: April 16, 2023
Citation
Auwaerter, Paul. "Other Atypical Mycobacteria." Johns Hopkins ABX Guide, The Johns Hopkins University, 2023. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540406/all/Other_atypical_mycobacteria.
Auwaerter P. Other atypical mycobacteria. Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540406/all/Other_atypical_mycobacteria. Accessed December 9, 2024.
Auwaerter, P. (2023). Other atypical mycobacteria. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540406/all/Other_atypical_mycobacteria
Auwaerter P. Other Atypical Mycobacteria [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. [cited 2024 December 09]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540406/all/Other_atypical_mycobacteria.
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