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Oseltamivir

Kathryn Dzintars, Pharm.D., BCPS, Paul A. Pham, Pharm.D.
Oseltamivir is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Uncomplicated acute illness due to influenza A and B infection in patients > 2 weeks of age and older who have been symptomatic for no more than 2 days.
    • Efficacy not established (by prospective trials) if symptom onset > 48h duration.
  • Prophylaxis of influenza in ages ≥ 1 yr of age.

NON-FDA APPROVED USES

  • Severe illness due to influenza A and B infection in immunocompromised and elderly pts who are hospitalized, even if > 48h symptoms--though limited data regarding efficacy 3 - 5 days post symptom onset.
  • The Centers for Disease Control and Prevention (CDC) and the American Academy of Pediatrics recommend the use of oseltamivir for prophylaxis in infants > 3 months of age.

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Last updated: July 2, 2016

Citation

Dzintars, Kathryn, and Paul A Pham. "Oseltamivir." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540403/all/Oseltamivir.
Dzintars K, Pham PA. Oseltamivir. Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540403/all/Oseltamivir. Accessed April 21, 2019.
Dzintars, K., & Pham, P. A. (2016). Oseltamivir. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540403/all/Oseltamivir
Dzintars K, Pham PA. Oseltamivir [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 April 21]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540403/all/Oseltamivir.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Oseltamivir ID - 540403 A1 - Dzintars,Kathryn,Pharm.D., BCPS AU - Pham,Paul,Pharm.D. Y1 - 2016/07/02/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540403/all/Oseltamivir PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -