Oral Candidiasis

Shmuel Shoham, M.D.
Oral Candidiasis is a topic covered in the Johns Hopkins ABX Guide.

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PATHOGENS

  • Candida albicans
    • This is the dominant organism in oral candidiasis (~80% of colonizing isolates).
      • C. albicans may cause infection alone or in combination with non-C. albicans species.
    • Typically susceptible to azole antifungals, but resistance can develop.
  • Non-albicans Candida spp
    • Most common non-C. albicans organisms: C. glabrata,C. tropicalis, C. dubliniensis and C. krusei.
    • C. glabrata may occur as part of a mixed infection (along with C. albicans) and can cause fluconazole refractory infections, some of which can prove resistant to other azoles as well.

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PATHOGENS

  • Candida albicans
    • This is the dominant organism in oral candidiasis (~80% of colonizing isolates).
      • C. albicans may cause infection alone or in combination with non-C. albicans species.
    • Typically susceptible to azole antifungals, but resistance can develop.
  • Non-albicans Candida spp
    • Most common non-C. albicans organisms: C. glabrata,C. tropicalis, C. dubliniensis and C. krusei.
    • C. glabrata may occur as part of a mixed infection (along with C. albicans) and can cause fluconazole refractory infections, some of which can prove resistant to other azoles as well.

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Last updated: February 8, 2020