Johns Hopkins ABX Guide
Norovirus
MICROBIOLOGY
- Small, non-enveloped, single-stranded positive-sense RNA virus.
- Noroviruses are 1 of 5 genera in the Caliciviridae family.
- Sapoviruses are another genus in the family that also cause acute gastroenteritis.
- Noroviruses are grouped into genogroups, numbering six currently known (I, II, and IV cause human infections), further divided into genetic clusters.
- Genogroup II, genotype 4 (II.4) is most commonly associated with outbreaks and severe disease.
- Genogroup I generally causes less severe disease and a lower attack rate partly because of an association between ABO blood type and infection.
- A total of 25 genotypes are known among GI, GII and GIV.
- Previously known as "Norwalk-like viruses."
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Last updated: September 10, 2023
Citation
Hoffmann, Christopher J. "Norovirus." Johns Hopkins ABX Guide, The Johns Hopkins University, 2023. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540392/all/Norovirus.
Hoffmann CJ. Norovirus. Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540392/all/Norovirus. Accessed November 23, 2024.
Hoffmann, C. J. (2023). Norovirus. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540392/all/Norovirus
Hoffmann CJ. Norovirus [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. [cited 2024 November 23]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540392/all/Norovirus.
* Article titles in AMA citation format should be in sentence-case
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T1 - Norovirus
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PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
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