Norovirus

Christopher J. Hoffmann, M.D., M.P.H.
Norovirus is a topic covered in the Johns Hopkins ABX Guide.

To view the entire topic, please or .

Pediatrics Central™ is an all-in-one application that puts valuable medical information, via your mobile device or the web, in the hands of clinicians treating infants, children, and adolescents. Explore these free sample topics:

-- The first section of this topic is shown below --

MICROBIOLOGY

  • Small, non-enveloped, single-stranded positive-sense RNA virus.
  • Noroviruses are 1 of 5 genera in the Caliciviridae family.
    • Sapoviruses are another genus in the family that also cause acute gastroenteritis.
  • Noroviruses are grouped into genogroups, numbering six currently known (I, II, and IV cause human infections), further divided into genetic clusters.
    • Genogroup II, genotype 4 (II.4) is most commonly associated with outbreaks and severe disease.
    • Genogroup I generally causes less severe disease and a lower attack rate partly because of an association between ABO blood type and infection.
    • Total 25 genotypes known among GI, GII and GIV.
  • Previously known as "Norwalk-like viruses."

-- To view the remaining sections of this topic, please or --

MICROBIOLOGY

  • Small, non-enveloped, single-stranded positive-sense RNA virus.
  • Noroviruses are 1 of 5 genera in the Caliciviridae family.
    • Sapoviruses are another genus in the family that also cause acute gastroenteritis.
  • Noroviruses are grouped into genogroups, numbering six currently known (I, II, and IV cause human infections), further divided into genetic clusters.
    • Genogroup II, genotype 4 (II.4) is most commonly associated with outbreaks and severe disease.
    • Genogroup I generally causes less severe disease and a lower attack rate partly because of an association between ABO blood type and infection.
    • Total 25 genotypes known among GI, GII and GIV.
  • Previously known as "Norwalk-like viruses."

There's more to see -- the rest of this topic is available only to subscribers.

Last updated: September 16, 2019