Johns Hopkins ABX Guide
Mycobacterium scrofulaceum
Mycobacterium scrofulaceum is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- Slow-growing acid fast bacilli (AFB), nontubercular Mycobacterium (NTM).
- Runyon classification Group 2: scotochromogen (meaning develops yellow-orange pigment in either the light or the dark; other members include M. szulgai, M. gordonae).
- Worldwide distribution; the reservoir is soil and water.
- AFB smear appearance is thicker and longer than M. tuberculosis, but definitive identification depends on culture.
- Differentiation from other NTM may be difficult.
- DNA probes or 16s ribosomal sequencing are helpful.
- Newly described M. parascrofulaceum may account for many clinical isolates. Difficult to distinguish in the lab from M. scrofulaceum.
- Most closely related to M. simiae.
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MICROBIOLOGY
- Slow-growing acid fast bacilli (AFB), nontubercular Mycobacterium (NTM).
- Runyon classification Group 2: scotochromogen (meaning develops yellow-orange pigment in either the light or the dark; other members include M. szulgai, M. gordonae).
- Worldwide distribution; the reservoir is soil and water.
- AFB smear appearance is thicker and longer than M. tuberculosis, but definitive identification depends on culture.
- Differentiation from other NTM may be difficult.
- DNA probes or 16s ribosomal sequencing are helpful.
- Newly described M. parascrofulaceum may account for many clinical isolates. Difficult to distinguish in the lab from M. scrofulaceum.
- Most closely related to M. simiae.
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Last updated: January 23, 2023
Citation
Auwaerter, Paul. "Mycobacterium Scrofulaceum." Johns Hopkins ABX Guide, The Johns Hopkins University, 2023. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540369/all/Mycobacterium_scrofulaceum.
Auwaerter P. Mycobacterium scrofulaceum. Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540369/all/Mycobacterium_scrofulaceum. Accessed March 24, 2023.
Auwaerter, P. (2023). Mycobacterium scrofulaceum. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540369/all/Mycobacterium_scrofulaceum
Auwaerter P. Mycobacterium Scrofulaceum [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. [cited 2023 March 24]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540369/all/Mycobacterium_scrofulaceum.
* Article titles in AMA citation format should be in sentence-case
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PB - The Johns Hopkins University
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