Mycobacterium scrofulaceum

Mycobacterium scrofulaceum is a topic covered in the Johns Hopkins ABX Guide.

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  • Slow-growing acid fast bacilli (AFB), nontubercular mycobacterium (NTM).
    • Runyon classification Group 2: scotochromogen (meaning develops yellow-orange pigment in either the light or the dark; other members include M. szulgai, M. gordonae).
  • World-wide distribution; reservoir is soil, water.
  • AFB smear appearance is thicker, longer than M. tuberculosis but definitive identification depends on culture.
    • Differentiation from other NTM may be difficult.
    • DNA probes or 16s ribosomal sequencing useful.
  • Newly described M. parascrofulaceum may account for many clinical isolates. Difficult to distinguish in lab from M. scrofulaceum.
    • Most closely related to M. simiae.
    • Few human cases makes advice about treatment uncertain.

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Last updated: April 5, 2016