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Mycobacterium scrofulaceum

Mycobacterium scrofulaceum is a topic covered in the Johns Hopkins ABX Guide.

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  • Slow-growing acid fast bacilli (AFB), nontubercular mycobacterium (NTM).
    • Runyon classification Group 2: scotochromogen (meaning develops yellow-orange pigment in either the light or the dark; other members include M. szulgai, M. gordonae).
  • World-wide distribution; reservoir is soil, water.
  • AFB smear appearance is thicker, longer than M. tuberculosis but definitive identification depends on culture.
    • Differentiation from other NTM may be difficult.
    • DNA probes or 16s ribosomal sequencing useful.
  • Newly described M. parascrofulaceum may account for many clinical isolates. Difficult to distinguish in lab from M. scrofulaceum.
    • Most closely related to M. simiae.
    • Few human cases makes advice about treatment uncertain.

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Last updated: April 5, 2016


Auwaerter, Paul. "Mycobacterium Scrofulaceum." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540369/all/Mycobacterium_scrofulaceum.
Auwaerter P. Mycobacterium scrofulaceum. Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540369/all/Mycobacterium_scrofulaceum. Accessed April 24, 2019.
Auwaerter, P. (2016). Mycobacterium scrofulaceum. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540369/all/Mycobacterium_scrofulaceum
Auwaerter P. Mycobacterium Scrofulaceum [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 April 24]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540369/all/Mycobacterium_scrofulaceum.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Mycobacterium scrofulaceum ID - 540369 A1 - Auwaerter,Paul,M.D. Y1 - 2016/04/05/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540369/all/Mycobacterium_scrofulaceum PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -