Johns Hopkins ABX Guide
Mycobacterium avium-complex (MAC, MAI, non-HIV)
MICROBIOLOGY
- M. avium and M. intracellulare: slow-growing mycobacteria (10-21 days on solid media), often referred to as MAI complex.
- M. intracellulare: principally causes pulmonary disease.
- M. avium: more likely to cause disseminated disease (among immunocompromised people).
- M chimaera and several other sub-spp. also fits within MAC (see separate module).
- Environmental sources, especially water, are the reservoir for most human infections.
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Last updated: November 7, 2020
Citation
Hoffmann, Christopher J. "Mycobacterium Avium-complex (MAC, MAI, Non-HIV)." Johns Hopkins ABX Guide, The Johns Hopkins University, 2020. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540361/all/Mycobacterium_avium_complex__MAC__MAI__non_HIV_.
Hoffmann CJ. Mycobacterium avium-complex (MAC, MAI, non-HIV). Johns Hopkins ABX Guide. The Johns Hopkins University; 2020. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540361/all/Mycobacterium_avium_complex__MAC__MAI__non_HIV_. Accessed December 11, 2024.
Hoffmann, C. J. (2020). Mycobacterium avium-complex (MAC, MAI, non-HIV). In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540361/all/Mycobacterium_avium_complex__MAC__MAI__non_HIV_
Hoffmann CJ. Mycobacterium Avium-complex (MAC, MAI, Non-HIV) [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2020. [cited 2024 December 11]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540361/all/Mycobacterium_avium_complex__MAC__MAI__non_HIV_.
* Article titles in AMA citation format should be in sentence-case
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