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- Miltefosine is available under an expanded access IND form the CDC (770-488-7100) in the U.S. for the treatment of free-living ameba, including primary meningoencephalitis (PAM) caused by Naegleria fowleri and granulomatous amebic encephalitis (GAM) caused by Balamuthia mandrillaris and Acanthamoeba species.
- Treatment of cutaneous, mucosal, and visceral leishmaniasis in patients >12 years of age.
NON-FDA APPROVED USES
- Use in combination with voriconazole and terbinafine for the management of Scedosporium prolificans