Johns Hopkins ABX Guide
Imipenem/Cilastatin
INDICATIONS
FDA
FDA
- Skin/soft tissue infections (not MRSA)
- Lower respiratory tract infections (pneumonia, bronchitis, COPD exacerbations) caused by S. pneumoniaeand H. influenzae.
- Gynecologic infections
- Intra-abdominal infections (acute gangrenous or perforated appendicitis and appendicitis with peritonitis)
- Uncomplicated and complicated urinary tract infections (pyelonephritis)
- Bacterial endocarditis
- Bacterial septicemia
- Bone/joint infections
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Gas gangrene
- Diabetic foot infection
- MDR Gram-negative infections
- Nocardia infections
- Non-TB mycobacterial infections
- Melioidosis
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Last updated: January 11, 2025
Citation
, Caitlin Soto, PharmD, BCIDP. "Imipenem/Cilastatin." Johns Hopkins ABX Guide, The Johns Hopkins University, 2025. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540281/all/Imipenem_Cilastatin.
C. Imipenem/Cilastatin. Johns Hopkins ABX Guide. The Johns Hopkins University; 2025. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540281/all/Imipenem_Cilastatin. Accessed July 26, 2025.
, C. (2025). Imipenem/Cilastatin. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540281/all/Imipenem_Cilastatin
C. Imipenem/Cilastatin [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2025. [cited 2025 July 26]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540281/all/Imipenem_Cilastatin.
* Article titles in AMA citation format should be in sentence-case
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T1 - Imipenem/Cilastatin
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A1 - ,Caitlin Soto, PharmD, BCIDP,
Y1 - 2025/01/11/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540281/all/Imipenem_Cilastatin
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -
